松果体肽 Pinealon

理化性质

CAS 号

175175-23-2

作用与功效

作用机制与靶点

松果体提取短肽(Lys-Glu-Asp 三肽类):作用于松果体与下丘脑调节褪黑素分泌节律,保护神经元免受氧化损伤,延缓神经老化

功效说明

功效:松果体提取短肽;调节褪黑素分泌、稳定生物钟、延缓神经老化、改善情绪。

英文详细资料 / Details (EN)

英文简介 / Overview (EN)

Pinealon, also known as EDR peptide, is a synthetic tripeptide of sequence (Glu-Asp-Arg) and purported geroprotector documented in the Russian scientific literature. Pinealon is one of several tripeptide "bioregulators" developed in Russia.

Source: English Wikipedia, "Pinealon".

临床证据与安全性(英文)/ Clinical Evidence (EN)

Pinealon has been shown to protect rat offspring from prenatal hyperhomocysteinemia and correspondingly improve post natal cognitive function.

Pinealon likewise maintains learning retention rats with experimentally-induced diabetes.

^ Arutjunyan A, Kozina L, Stvolinskiy S, Bulygina Y, Mashkina A, Khavinson V (2012-04-06). "Pinealon protects the rat offspring from prenatal hyperhomocysteinemia". International Journal of Clinical and Experimental Medicine. 5 (2): 179–185. PMC 3342713. PMID 22567179.

^ Karantysh GV, Fomenko MP, Menzheritskii AM, Prokof'ev VN, Ryzhak GA, Butenko EV (July 2020). "Effect of Pinealon on Learning and Expression of NMDA Receptor Subunit Genes in the Hippocampus of Rats with Experimental Diabetes". Neurochemical Journal. 14 (3): 314–320. doi:10.1134/S181971242003006X. ISSN 1819-7132. S2CID 255382498.

功效:松果体提取短肽;调节褪黑素分泌、稳定生物钟、延缓神经老化、改善情绪。

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