聚乙二醇化机械生长因子 PEG-MGF

作用与功效

作用机制与靶点

聚乙二醇化的机械生长因子 / IGF-1Ec C 端剪接变体(机械生长因子 MGF)的 PEG 修饰版本:抗酶解延长半衰期,在肌纤维微损伤后激活肌肉卫星细胞(肌源性干细胞)增殖与融合

功效说明

在肌肉进行大重量抗阻力训练发生微小撕裂后,注射此多肽可招募卫星干细胞到损伤部位,促进局部肌纤维的高效修复与肥大。

英文详细资料 / Details (EN)

英文简介 / Overview (EN)

Note: This PeptideSCM entry is a related form of the subject; the overview below is from the English Wikipedia article "Mechano growth factor".

Mechano growth factor (MGF, IGF-IEc) is a naturally occurring 24-amino acid peptide which is the C-terminal fragment derived from enzymatic cleavage of insulin-like growth factor 1 (IGF-1). It is expressed during muscle repair following physical activity, and has anabolic effects. This has led to illicit use by athletes leading to MGF being banned by the World Anti-Doping Association.

At least one research paper raised concerns about the potential carcinogenicity of this compound.

Source: English Wikipedia, "Mechano growth factor".

在肌肉进行大重量抗阻力训练发生微小撕裂后,注射此多肽可招募卫星干细胞到损伤部位,促进局部肌纤维的高效修复与肥大。

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