线粒体靶向抗氧化肽 SS-31 / Elamipretide
理化性质
736992-21-5
作用与功效
线粒体靶向内膜修复剂 / 靶向线粒体内膜的芳香族阳离子四肽：选择性结合心磷脂（cardiolipin）稳定呼吸链超复合物、恢复 ATP 产能并减少活性氧泄漏，修复线粒体结构与功能
功效：定向保护线粒体，清除细胞氧化自由基；抗细胞衰老、减轻氧化损伤；保护心肌、脑神经、皮肤细胞，缓解疲劳、抗炎。
选择性结合线粒体内膜的心磷脂，修复线粒体结构并恢复细胞 ATP 产能，对抗氧化应激、心脏衰竭及深层器官衰竭。
英文详细资料 / Details (EN)
Elamipretide, sold under the brand name Forzinity, is a medication used for the treatment of Barth syndrome. Elamipretide is a mitochondrial cardiolipin binder. It is used as the hydrochloride salt. It is given by injection under the skin (subcutaneous).
The most common side effects identified in clinical trials include mild-to-moderate injection site reactions.
Elamipretide was approved for medical use in the United States in September 2025. The US Food and Drug Administration considers it to be a first-in-class medication.
Source: English Wikipedia, "Elamipretide".
功效：定向保护线粒体，清除细胞氧化自由基；抗细胞衰老、减轻氧化损伤；保护心肌、脑神经、皮肤细胞，缓解疲劳、抗炎。
选择性结合线粒体内膜的心磷脂，修复线粒体结构并恢复细胞 ATP 产能，对抗氧化应激、心脏衰竭及深层器官衰竭。